Membrane stress caused by octanoic acid in Saccharomyces cerevisiae

Alteration in membrane fluidity and lipid composition, and modulation of H(+)-ATPase activity in Saccharomyces cerevisiae caused by decanoic acid.

Decanoic acid, a lipophilic agent, inhibited in vitro the plasma membrane H(+)-ATPase of Saccharomyces cerevisiae grown in YPD medium. Conversely, when decanoic acid (35 microM) was present in the growth medium, the measured H(+)-ATPase activity was four times higher than that of control cells. Km, and pH and orthovanadate sensitivity were the same for the two growth conditions, which indicated...

Global analysis of genomic instability caused by DNA replication stress in Saccharomyces cerevisiae.

DNA replication stress (DRS)-induced genomic instability is an important factor driving cancer development. To understand the mechanisms of DRS-associated genomic instability, we measured the rates of genomic alterations throughout the genome in a yeast strain with lowered expression of the replicative DNA polymerase δ. By a genetic test, we showed that most recombinogenic DNA lesions were intr...

Catheter-related fungemia caused by Saccharomyces cerevisiae in a newborn.

Fluidization of Membrane Lipids Enhances Tolerance of Freezing and Salt Stress by Saccharomyces cerevisiae

Signalling Oxidative Stress in Saccharomyces cerevisiae